In 2001, Benedetto et al. revealed that Central Asian genetic contribution to the current Anatolian mtDNA gene pool was estimated as roughly 30%, by comparing the populations of Mediterranean Europe , and Turkic-speaking people of Central Asia .  However some similar early studies have a high probability of errors and biased estimates, which concluded even up to over 60% Central Asian origin of Y-DNA microsatellites.  In 2003, Cinnioğlu et al. made a research of Y-DNA including the samples from eight regions of Turkey, without classifying the ethnicity of the people, which indicated that high resolution SNP analysis totally provides evidence of a detectable weak signal (<9%) of gene flow from Central Asia, but this was an underestimate summarizing only haplogroups C, Q, O and N.  It was later observed that the male contribution from Central Asia to Turkish population with reference to the Balkans was 13%, for all non-Turkic speaking populations the Central Asian contribution was higher than in Turkey.  According to the study "the contributions ranging between 13%–58% must be considered with a caution because they harbor uncertainties about the state of pre-nomadic invasion and further local movements." A 2001 study concluded that the Central Asian contribution to Anatolia for Y-DNA is 12%, mtDNA 22%, alu insertion (autosomal) 15%, autosomal 22%, with respect to Kyrgyzstan, Kazakhstan, Uyghur, Turkmenistan, Uzbekistan.  By that method, for Y-DNA, Alu, mtDNA except Iraq (13%) and Armenia (6%) for females, the Central Asian contribution to the hybrids (Armenia, Georgia, Northern Caucasus, Syria, Iran, Iraq, Lebanon) were similar or even higher than to those of Turkey and Azerbaijan.
Impedance -based single cell analysis systems are commonly known as Coulter counters . They represent a well-established method for counting and sizing virtually any kind of cells and particles. The label-free technology has recently been enhanced by a " lab-on-a-chip " based approach and by applying high frequency alternating current (AC) in the radio frequency range (from 100 kHz to 30 MHz) instead of a static direct current (DC) or low frequency AC field.  This patented technology allows a highly accurate cell analysis and provides additional information like membrane capacitance and viability . The relatively small size and robustness allow battery powered on-site use in the field.
We may examine representative incidents by following the geographic route of European settlement, beginning in the New England colonies. There, at first, the Puritans did not regard the Indians they encountered as natural enemies, but rather as potential friends and converts. But their Christianizing efforts showed little success, and their experience with the natives gradually yielded a more hostile view. The Pequot tribe in particular, with its reputation for cruelty and ruthlessness, was feared not only by the colonists but by most other Indians in New England. In the warfare that eventually ensued, caused in part by intertribal rivalries, the Narragansett Indians became actively engaged on the Puritan side.